Royal Air Force Typhoon FGR4s have conducted a mission with French warplanes in a joint strike targeting an hidden munitions depot in Syria operated by the IS group, per a report from the British defence ministry.
The location, pinpointed through surveillance, was assessed as storing arms and explosives, the announcement noted, and was located in mountainous terrain just north of Palmyra in central Syria.
"Our fighter planes utilized precision-guided Paveway IV munitions to hit a number of entry passages down to the facility... initial indications are that the objective was successfully hit," officials stated.
There was no sign of any civilian impact in the attack late on Saturday and every plane involved returned to base without incident, the ministry further stated.
The British jets were supported by a Voyager aerial refuelling aircraft.
IS - referred to as the so-called Islamic State - established jihadist rule over significant areas in Iraq and Syria before its territorial defeat in 2019.
"This strike demonstrates British leadership, and commitment to stand shoulder to shoulder with allied nations, to stamp out any revival of Daesh and their dangerous and violent ideologies in the region," the British Defence Secretary John Healey stated.
UK warplanes have carried out overwatch operations over Syrian airspace to "forestall any attempted resurgence" of IS after its defeat at the climactic battle in Baghuz in 2019, the ministry said.
"I extend gratitude to every member of the UK armed forces involved in this mission for their professionalism and their valour," the Defence Secretary said. "They were among a great many British troops stationed over Christmas and New Year. This action, to eliminate terrorist threats who threaten our way of life, shows how our armed forces are always on standby, throughout the year, ensuring Britain's security at home and strong abroad."
Last December, the US military conducted what it called a "large-scale strike" targeting Daesh sites in the country, subsequent to an ambush claimed the lives of two US servicemembers and a civilian linguist in the Palmyra area.
The UN estimates IS still maintains between 5,000 and 7,000 fighters in Syria and Iraq.